Basic information about sleep physiology and circadian processes; no medical advice.
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Which is the deepest sleep stage in humans?
- NREM Stage 1
- REM sleep
- NREM Stage 2
- NREM Stage 3
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D) NREM Stage 3
Which brain structure is the main central regulator of circadian rhythms in mammals?
- Dentate nucleus
- Caudate nucleus
- Subthalamic nucleus
- Suprachiasmatic nucleus
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D) Suprachiasmatic nucleus
Which substance builds up in the brain during wakefulness and is associated with sleep pressure?
- Adenosine
- Melatonin
- Cortisol
- Serotonin
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A) Adenosine
Which defining feature gives REM sleep its name?
- Slow-wave activity
- Slow eye movements
- Rapid eye movements
- Increased muscle tone
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C) Rapid eye movements
About how many hours long is the human internal circadian period?
- 26 hours
- 25 hours
- 24 hours
- 23 hours
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C) 24 hours
Which pathway carries retinal light information to the circadian clock?
- Medial lemniscus
- Optic tract
- Corticospinal tract
- Retinohypothalamic tract
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D) Retinohypothalamic tract
As of 2026, how many stages are in the AASM sleep-stage classification?
- 3
- 2
- 4
- 5
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C) 4
What is the name for temporary circadian misalignment associated with rapidly crossing multiple time zones?
- Delayed sleep-wake phase
- Jet lag
- Shift-work schedule
- Advanced sleep-wake phase
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B) Jet lag
In a sleep cycle, which broad type of sleep usually occurs before a REM period?
- NREM sleep
- REM sleep
- Wakefulness
- Brief awakening
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A) NREM sleep
How can using a light-emitting screen in the evening generally affect melatonin secretion?
- Leave it unchanged
- Suppress it
- Increase it
- Advance it
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B) Suppress it
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